… obstruction (UUO)-induced renal fibrosis in vivo and TGF-β1-induced … GS-HCl decreased
the elevated TGF-β signaling in renal fibrosis. Further, we presented a mechanism that GS-HCl …

… the effect of blockade of endogenous CTGF on TGF-β-… into cultured renal fibroblasts
significantly attenuated TGF-β-… Besides stimulating fibrogenesis, CTGF exerts various biological …

… F2 was most effective in attenuating hyperglycemia and insulin … F2 and FR exerted significant
effects to decrease DPP-4 but … by inhibiting N-linked glycosylation of the TGF-β receptor, …

… against unilateral ureteral obstruction-induced renal fibrosis, … TGF-β-induced ROS generation
through a TGF-β/Smad/ROS … Nrf2 activity could effectively attenuate fibrogenesis in animal …

… a Structure of glucosamine hydrochloride b Greatly … embryonic kidney-293 cell line exhibited
reduced TGF-β signaling … Should we commence with trials of glucosamine for renal fibrosis …

… and cell survival and have protective effects at the cellular, … GlcNAc-modified proteins but
also through attenuation of NF-κB … glucosamine hydrochloride is an obstacle to TGF-β signaling…

… evidences associate glycosylation modification with TGF-β signaling pathway, and we can
… the activation of TGF-β/Smad2/3 signaling and attenuated UUO-induced renal fibrosis [92]. …

… with N1 significantly attenuated phosphorylation of both STAT3 … N1 exerts anti-fibrotic and
anti-inflammatory effects through … roles in relaying extracellular TGF-β signals, and that Smad3 …

… whether GlcN affects signaling via TGF-β receptors (TGF-βRs… in human renal epithelial cells
to attenuate TGF-β signaling [… epithelial cells exerts diverse effects during renal fibrosis and …

… fibrosis were attenuated. XJEK also decreased SCR, BUN, urinary proteins in 24h urine, serum
Ang II and TGF-β 1 concentrations and the intra-renal TGF-β … The protective effect is most …